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journalArticle
Hoogduijn
M. J.
Popp
F. C.
Grohnert
A.
Crop
M. J.
van Rhijn
M.
Rowshani
A. T.
Eggenhofer
E.
Renner
P.
Reinders
M. E.
Rabelink
T. J.
van der Laan
L. J.
Dor
F. J.
Ijzermans
J. N.
Genever
P. G.
Lange
C.
Durrbach
A.
Houtgraaf
J. H.
Christ
B.
Seifert
M.
Shagidulin
M.
Donckier
V.
Deans
R.
Ringden
O.
Perico
N.
Remuzzi
G.
Bartholomew
A.
Schlitt
H. J.
Weimar
W.
Baan
C. C.
Dahlke
M. H.
Group
Misot Study
Cell
Cells/cytology/immunology/physiology
Culture
Graft
Humans
Immunophenotyping
Immunosuppression/methods
Kidney
Liver
Mesenchymal
Organ
Safety
Stem
Stromal
Survival/*physiology
T-Lymphocytes/immunology
Techniques
Therapy/methods
Tissue
Transplantation/*methods
Transplantation/*methods/physiology
Transplantation/immunology/physiology
Advancement of mesenchymal stem cell therapy in solid organ transplantation (MISOT)
There is evolving interest in the use of mesenchymal stem cells (MSC) in solid organ transplantation. Pre-clinical transplantation models show efficacy of MSC in prolonging graft survival and a number of clinical studies are planned or underway. At a recent meeting of the MISOT consortium (MSC In Solid Organ Transplantation) the advances of these studies were evaluated and mechanisms underlying the potential effects of MSC discussed. Continued discussion is required for definition of safety and eventually efficacy endpoints for MSC therapy in solid organ transplantation.
124-6
Jul 27 2010
Advancement of mesenchymal stem cell therapy in solid organ transplantation (MISOT)
http://www.ncbi.nlm.nih.gov/pubmed/20606604
Transplantation
90
2
ISSN 1534-6080 (ELECTRONIC) 0041-1337 (LINKING)