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journalArticle Hoogduijn M. J. Popp F. C. Grohnert A. Crop M. J. van Rhijn M. Rowshani A. T. Eggenhofer E. Renner P. Reinders M. E. Rabelink T. J. van der Laan L. J. Dor F. J. Ijzermans J. N. Genever P. G. Lange C. Durrbach A. Houtgraaf J. H. Christ B. Seifert M. Shagidulin M. Donckier V. Deans R. Ringden O. Perico N. Remuzzi G. Bartholomew A. Schlitt H. J. Weimar W. Baan C. C. Dahlke M. H. Group Misot Study Cell Cells/cytology/immunology/physiology Culture Graft Humans Immunophenotyping Immunosuppression/methods Kidney Liver Mesenchymal Organ Safety Stem Stromal Survival/*physiology T-Lymphocytes/immunology Techniques Therapy/methods Tissue Transplantation/*methods Transplantation/*methods/physiology Transplantation/immunology/physiology Advancement of mesenchymal stem cell therapy in solid organ transplantation (MISOT) There is evolving interest in the use of mesenchymal stem cells (MSC) in solid organ transplantation. Pre-clinical transplantation models show efficacy of MSC in prolonging graft survival and a number of clinical studies are planned or underway. At a recent meeting of the MISOT consortium (MSC In Solid Organ Transplantation) the advances of these studies were evaluated and mechanisms underlying the potential effects of MSC discussed. Continued discussion is required for definition of safety and eventually efficacy endpoints for MSC therapy in solid organ transplantation. 124-6 Jul 27 2010 Advancement of mesenchymal stem cell therapy in solid organ transplantation (MISOT) http://www.ncbi.nlm.nih.gov/pubmed/20606604 Transplantation 90 2 ISSN 1534-6080 (ELECTRONIC) 0041-1337 (LINKING)