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TY - JOUR
TI - Excellent survival after liver transplantation for isolated polycystic liver disease: an European Liver Transplant Registry study
AU - van Keimpema, L.
AU - Nevens, F.
AU - Adam, R.
AU - Porte, R. J.
AU - Fikatas, P.
AU - Becker, T.
AU - Kirkegaard, P.
AU - Metselaar, H. J.
AU - Drenth, J. P.
T2 - Transpl Int
AB - Patients with end-stage isolated polycystic liver disease (PCLD) suffer from incapacitating symptoms because of very large liver volumes. Liver transplantation (LT) is the only curative option. This study assesses the feasibility of LT in PCLD. We used the European Liver Transplant Registry (ELTR) database to extract demographics and outcomes of 58 PCLD patients. We used Kaplan-Meier survival analysis for survival rates. Severe abdominal pain (75%) was the most prominent symptom, while portal hypertension (35%) was the most common complication in PCLD. The explantation of the polycystic liver was extremely difficult in 38% of patients, because of presence of adhesions from prior therapy (17%). Karnofsky score following LT was 90%. The 1- and 5-year graft survival rate was 94.3% and 87.5%, while patient survival rate was 94.8% and 92.3%, respectively. Survival rates after LT for PCLD are good.
DA - 2011/12//
PY - 2011
VL - 24
IS - 12
SP - 1239
EP - 45
SN - 1432-2277 (ELECTRONIC); 0934-0874 (LINKING)
ST - Excellent survival after liver transplantation for isolated polycystic liver disease: an European Liver Transplant Registry study
KW - Adult
KW - Aged
KW - Cysts/diagnosis/surgery
KW - Diseases/diagnosis/surgery
KW - Estimate
KW - Europe/epidemiology
KW - Female
KW - Graft
KW - Humans
KW - Kaplan-Meier
KW - Liver
KW - Male
KW - Middle
KW - Outcome
KW - Registries
KW - Survival
KW - Transplantation/
KW - Treatment
KW - mortality/physiology
ER -